Perlane Review

Perlane Review

Perlane is a Hyaluronic Acid dermal filler that’s very similar to Restylane and is manufactured by the same company that manufacture Restylane®. Perlane® and Restylane® are both composed of hyaluronic acid. Perlane has larger gel particles and is intended to be injected deeper within the skin.

Perlane® is used to smooth moderate to severe facial folds and wrinkles such as the lines from the nose to the corners of the mouth (nasolabial folds). Perlane® generally lasts for about 6 months. It has been found to be a safe dermal filler that restores volume and fullness to the skin. Perlane® gradually disappears from the body without a trace.

Perlane® is injected into the skin with an ultrafine needle. It plumps the skin to smooth away wrinkles and folds. Perlane®’s water-binding nature attracts and binds water molecules to help maintain volume. Perlane® is composed of hyaluronic acid, a natural substance that already exists in the body. The hyaluronic acid in Perlane® is a crystal clear gel that is chemically cross-linked (the long chemical strands are tied together) to delay breakdown by skin enzymes. Perlane® is nonanimal-based and free from animal protein. This quality prevents disease transmission. Allergy pretesting is not necessary.

Perlane® was studied in multiple clinical studies. In one, treatment of the nasolabial folds with Perlane® resulted in an improvement in wrinkles in 137 of 149 patients after three months, and 105 of 148 patients after six months. In another study, treatment of nasolabial folds with Perlane® resulted in an improvement in wrinkles in 122 of 141 patients after three months, and 88 of 138 patients after six months. Side effects were mild. Most of the side effects went away in seven days. Perlane® did not cause allergic reactions.

Perlane® has been used safely by dermatologists and plastic surgeons since 2000 worldwide.


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