The primary mechanism of UV-induced skin aging is mediated by the generation and accumulation of free radicals including reactive oxygen species (ROS) and reactive nitrogen species (RNS). ROS or free radicals not only can damage proteins, DNA, cellular membrane and … Continue reading
The molecular signaling pathways associated with skin aging is most and initially studied in the photo skin aging. Numerous researches published combined the pieces of discovery into an general overview picture about what occurred molecularly in photo skin aging. It … Continue reading
The activator protein 1 (AP-1) is a heterodimeric transcription factor belonging to the c-Fos, c-Jun, ATF and JDP families. It regulates and activates genes in response to a variety of stimuli including stress, pathogen infections, cytokines, growth factors. AP-1 thereby … Continue reading