Tag Archives: fibroblast aging

Dermal Fibroblast DNA Methylation and Skin Aging

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Epigenetic modifications such as DNA methylation and histone modification play an important role for cellular senescence and aging including skin aging. DNA can be methylated at cytosine residue (CpG). DNA methylation  provide an mechanism for the regulation of programmed progressive … Continue reading →

The Role of Fibroblasts In Skin Aging

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Fibroblasts are the most common cells of connective tissue that synthesizes the extracellular matrix and play a critical role in wound healing. Fibroblasts make and secrete collagens, elastin, ground substances such as glycosaminoglycans, glycoproteins found in the extracellular matrix and … Continue reading →