Epigenetic modifications such as DNA methylation and histone modification play an important role for cellular senescence and aging including skin aging. DNA can be methylated at cytosine residue (CpG). DNA methylation provide an mechanism for the regulation of programmed progressive … Continue reading
Fibroblasts are the most common cells of connective tissue that synthesizes the extracellular matrix and play a critical role in wound healing. Fibroblasts make and secrete collagens, elastin, ground substances such as glycosaminoglycans, glycoproteins found in the extracellular matrix and … Continue reading
What is Collagen Collagen, a group of naturally occurring proteins and the main component of connective tissue, is the most abundant protein making up 25% to 35% of the whole-body protein content. Collagen fibers (fine fibers about 1 nm in … Continue reading