UV-Induced Neutrophil Infiltration and Increased MMP Secretion in Photo Skin Aging

The primary mechanism of photo skin aging is mediated by UV induced reactive oxygen species (ROS). ROS damages biomacromolecules and function as intracellular signal to activate transcription factors AP-1 and NF-kB . AP-1 And NF-kB are known to regulate a … Continue reading

NF-kB and AP-1 Molecular Signaling Mechanisms of Intrinsic And Extrinsic Skin Aging

The molecular signaling pathways associated with skin aging is most and initially studied in the photo skin aging. Numerous researches published combined the pieces of discovery into an general overview picture about what occurred molecularly in photo skin aging. It … Continue reading