The Effect of UV-Induced Gene Activation On Photo Skin Aging

The primary mechanism of UV-induced skin aging is mediated by the generation and accumulation of free radicals including reactive oxygen species (ROS) and reactive nitrogen species (RNS). ROS or free radicals not only can damage proteins, DNA, cellular membrane and … Continue reading

NF-kB and AP-1 Molecular Signaling Mechanisms of Intrinsic And Extrinsic Skin Aging

The molecular signaling pathways associated with skin aging is most and initially studied in the photo skin aging. Numerous researches published combined the pieces of discovery into an general overview picture about what occurred molecularly in photo skin aging. It … Continue reading

Is NF-kB the Secret to Skin Aging?

NF-κB is a protein complex that controls the transcription of DNA know as transcription factor which in turn regulate the expression of various genes. NF-κB is found in almost all cell types and is involved in cellular responses to stimuli … Continue reading