The Mechanism of Stem Cell Therapy of Peptide 199 In CytoCell Skin Care Line

Peptide 199 is a stem cell ingredients heavily used in Kate Somerville’s CytoCell anti-aging skin care line. Peptide 199 is an amino acid chain derived from the Wharton Jelly in the umbilical cord. Wharton’s jelly is a gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate) as well as some fibroblasts and macrophages. Wharton’s jelly is a potential source of adult stem cells. Cells in Wharton’s jelly also express several stem cell genes, including telomerase.

Peptide 199 stimulates activity in the skin stem cells, making the adult stem cell’s repair function become similar to fetal skin healing process. The fetal skin heals via a completely different mechanism to that of adult skin repair process. Adult skin respond to tissue damage mainly via an inflammatory process mechanism, involving activations of macrophages and type 1 collagen. In contrast, fetal skin, when it is healing, activates mainly skin’s stem cells and fibroblasts. In addition, one of the most important differences between adult and fetal skin repair and renewal process is that fetal skin heals without scarring. For this reason, scientists have been looking for ingredients of embryonic or fetal source that will work in a way to mimic the fetal skin healing process . Peptide 199, a gelatinous substance found in the umbilical cord ensures the dominance of stem cell and fibroblast response over the inflammatory process, mimicking the fetal skin repair process without a scar or wrinkle.

Kate Somerville’s CytoCell Line of Products (CytoCell Dermal Energizing Treatment, CytoCell Dark Circle Corrective Eye Cream) is all about new skin cell creation. All of that translates to fresh, revitalized youthful, radiant, healthy skin on the whole.


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