The Histological Changes And The Clinical Features That Characterize Chronological Skin Aging and PhotoAging

The chronological skin aging is driven by the genetic programming – the programmed aging process that also makes the hair white and makes the teeth fall -. When the natural aging process is superimposed with photodamage, the skin ages much … Continue reading

Enhanced Expression of Cylooxygenase-2(COX-2) In Chronological Skin Aging And Photoaging

Skin aging can be attributed to photoaging (extrinsic) and chronological (intrinsic) aging. Photoaging and intrinsic aging are induced by damage to human skin attributable to repeated exposure to ultraviolet (UV) irradiation and to the passage of time. COX-2 is a … Continue reading

Is NF-kB the Secret to Skin Aging?

NF-κB is a protein complex that controls the transcription of DNA know as transcription factor which in turn regulate the expression of various genes. NF-κB is found in almost all cell types and is involved in cellular responses to stimuli … Continue reading

Inflammaging In Skin

Without inflammation, infections would go unchecked and wounds would not heal; however, the process of inflammation and repair can also be harmful. As we age, the immune system becomes less effective and its capacity to manage the inflammatory activity is … Continue reading

Gene Chip Technology In Identifying Pathways and Processes in Chronological Skin Aging and Photodamaged Skin

A DNA microarray (also commonly known as DNA chip or gene chip technology) is a collection of microscopic DNA spots attached to a solid surface. Each DNA spot contains picomoles (10−12 moles) of a specific DNA sequence called probes. Probes … Continue reading

Why Antioxidants Also Provide Anti-Inflammatory Protection For The Skin?

Antioxidants are a group of important ingredients for anti-aging skin care because of their ability to neutralize the free radical damage of cells and macromolecules (protein, DNA, lipids). – Free radical damage was one of the first processes associated with … Continue reading