The Effect of UV-Induced Gene Activation On Photo Skin Aging

The primary mechanism of UV-induced skin aging is mediated by the generation and accumulation of free radicals including reactive oxygen species (ROS) and reactive nitrogen species (RNS). ROS or free radicals not only can damage proteins, DNA, cellular membrane and … Continue reading

NF-kB and AP-1 Molecular Signaling Mechanisms of Intrinsic And Extrinsic Skin Aging

The molecular signaling pathways associated with skin aging is most and initially studied in the photo skin aging. Numerous researches published combined the pieces of discovery into an general overview picture about what occurred molecularly in photo skin aging. It … Continue reading

Structural, Histological And Clinical Changes In Chronologic Aged Skin And Photoaged Skin

Many of facial skin aging changes are not the inevitable result of chronologic aging, but with the accumulation of chronic environmental factors. The structural (molecular, cellular), histological changes and the clinical signs associated with intrinsic (chronological aging) and photoaging are … Continue reading

The Histological Changes And The Clinical Features That Characterize Chronological Skin Aging and PhotoAging

The chronological skin aging is driven by the genetic programming – the programmed aging process that also makes the hair white and makes the teeth fall -. When the natural aging process is superimposed with photodamage, the skin ages much … Continue reading