The molecular signaling pathways associated with skin aging is most and initially studied in the photo skin aging. Numerous researches published combined the pieces of discovery into an general overview picture about what occurred molecularly in photo skin aging. It … Continue reading
The activator protein 1 (AP-1) is a heterodimeric transcription factor belonging to the c-Fos, c-Jun, ATF and JDP families. It regulates and activates genes in response to a variety of stimuli including stress, pathogen infections, cytokines, growth factors. AP-1 thereby … Continue reading
Tissue inhibitor of metalloproteinases (TIMP) is a group of endogenous enzymes that inhibit the activity of matrix metalloproteinases (MMPs), which is a group of peptidases involved in degradation of the extracellular matrix. . There are four different TIMP identified – … Continue reading