NF-kB and AP-1 Molecular Signaling Mechanisms of Intrinsic And Extrinsic Skin Aging

The molecular signaling pathways associated with skin aging is most and initially studied in the photo skin aging. Numerous researches published combined the pieces of discovery into an general overview picture about what occurred molecularly in photo skin aging. It … Continue reading

Enhanced Expression of Cylooxygenase-2(COX-2) In Chronological Skin Aging And Photoaging

Skin aging can be attributed to photoaging (extrinsic) and chronological (intrinsic) aging. Photoaging and intrinsic aging are induced by damage to human skin attributable to repeated exposure to ultraviolet (UV) irradiation and to the passage of time. COX-2 is a … Continue reading

Is NF-kB the Secret to Skin Aging?

NF-κB is a protein complex that controls the transcription of DNA know as transcription factor which in turn regulate the expression of various genes. NF-κB is found in almost all cell types and is involved in cellular responses to stimuli … Continue reading

Inflammaging In Skin

Without inflammation, infections would go unchecked and wounds would not heal; however, the process of inflammation and repair can also be harmful. As we age, the immune system becomes less effective and its capacity to manage the inflammatory activity is … Continue reading