The dermal epidermal junction (DEJ) in the skin is the layer responsible for supporting the epidermis and epidermal-dermal adhesion and for the communication between epidermal and dermal cells. Traditionally, the study of the mechanisms of skin aging has overlooked this … Continue reading
Fibronectin is a glycoprotein of the extracellular matrix that binds to extracellular matrix components such as collagen, fibrin, heparan sulfate proteoglycans (e.g. syndecans) and membrane-spanning receptor proteins called integrins. Fibronectin exists as a protein dimer, consisting of two nearly identical … Continue reading