Anti-Aging Peptide Ingredients
– DERMICAN™ (Acetyl Tetrapeptide-9)
Dermican™ is manufactured by Laboratoires Sérobiologiques (LS) which is Cognis Care Chemicals’ active ingredients business. It specializes in the development, manufacture and marketing of innovative cosmetic concepts and active ingredients. INCI Name of Dermican™ is: Water, glycerin, acetyl tetrapeptide-9.
Dermican keeps skin looking and feeling younger by using a targeted mechanism to optimize the functionality of collagen fibers. Dermican™ is a pure tetrapeptide, developed with a single objective – to optimize the functionality of collagen fibers via an original mechanism of action that ensures proper anchoring of the collagen fibrils. It gets as close as is currently possible to recreating the physiology of younger skin, making users both look and feel more youthful.
Boosting collagen synthesis has been recognized as a key approach in anti-aging for some time now. Boosting collagen synthesis only is not sufficient to claim a thorough anti-aging approach: special attention should be paid to the structure of these new collagen fibers and their organization to ensure optimal skin mechanical properties. Research into the subject of skin aging has revealed that the way the collagen fibrils are organized is just as important in keeping skin youthful as the total number of them.
In young skin Extra-Cellular Matrix (ECM) is partly composed of collagen fibers formed by correct association of collagen fibrils. The efficient binding of collagen fibrils is initiated and regulated by some components including small molecules called proteoglycans (a protein-sugar complex) that attach themselves to the collagen fibrils and link them together, reducing the space in-between the fibrils, to form functional collagen fibers. Scientific research has highlighted the crucial role that proteoglycansplay in organizing collagen fibers, and consequently in maintaining the integrity of the extra-cellular matrix (ECM). Among the small proteoglycans, lumican plays an important role – it is involved in both the synthesis of collagen fibrils and their organization into functional fibers, ensuring the integrity of the extra-cellular matrix. The study also showed that the synthesis of this proteoglycan slows down with age. resulting in a loss of organization of the collagen fibers.