Tag Archives: collagen fibrillogenesis

Structural Change In Decorin With Skin Aging

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Decorin is an extracellular matrix proteoglycan belonging to the small leucine-rich proteoglycan (SLRP) family with a protein core containing leucine repeats with a glycosaminoglycan (GAG) chain of either chondroitin sulfate (CS) or dermatan sulfate (DS). Decorin, together with versican (bind … Continue reading →

Age-Related Changes in The Proteoglycans of Skin

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The dermis of skin is a connective tissue that contains an extensive extracellular matrix (ECM) whose biophysical properties are determined primarily by this matrix. Although collagen and elastin are the major extracellular matrix molecules of the dermis that provide skin … Continue reading →