Hyaluronan (also called hyaluronic acid or hyaluronate or HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. Hyaluronan is a polymer of disaccharides which is composed of D-glucuronic acid and D-N-acetylglucosamine. In the dermal connective … Continue reading
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The ground substance occupies the space between the cells and fibers of dermal connective tissues. It is an amorphous viscoelastic gel in which the other components (cells and fibers) are held in place . Ground substance consists largely of proteoglycans … Continue reading
The dermis of skin is a connective tissue that contains an extensive extracellular matrix (ECM) whose biophysical properties are determined primarily by this matrix. Although collagen and elastin are the major extracellular matrix molecules of the dermis that provide skin … Continue reading